Giant posterior mediastinal liposarcoma presenting as dysphagia: A clinico–radio– pathologic correlation

Oncology, Gastroenterology and Hepatology Reports,2014,3,2,43-45.
Published:July 2014
Type:Case Report
Author(s) affiliations:

Santosh P V Rai, Preetham Acharya1, Rameshchandra Sahoo1, Hema Kini2, Sharada Rai2, Maryann Bokelo2

Departments of Radiodiagnosis, 1Chest Medicine and 2Pathology, Kasturba Medical College, Unit of Manipal University, Mangalore, Karnataka, India


We report the rare case of a giant liposarcoma of the posterior mediastinum presenting with symptoms of dysphagia and esophageal reflux due to extrinsic compression. A contrast‑enhanced computed tomogram (CT) of the chest revealed a large fat density mass in the mid and posterior mediastinum. CT‑guided biospy showed vacuolated cells (lipoblasts) with marked nuclear atypia and indistinct cytoplasmic membrane and hyperchromatic nuclei suggesting liposarcoma.