Acute Promyelocytic Leukaemia(APML) in an Adult Patient Presenting with Multiple Lytic Bony Lesions – The First of its Kind – A Case Report with Review of Literature

Submitted by sysadmin1 on Wed, 02/22/2017 - 15:58
Oncology, Gastroenterology and Hepatology Reports,2017,6,2,80-82.
Published:February 2017
Type:Case Report

Acute Promyelocytic Leukaemia(APML) in an Adult Patient Presenting with Multiple Lytic Bony Lesions – The First of its Kind – A Case Report with Review of Literature

Rajeev Lakkavalli Krishnappa, Govinda Babu Kanakasetty, Suresh Babu Mallekavu Chikkadasappa, Suparna Ajit Rao*

Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, INDIA.

Abstract:

Acute promyelocytic leukaemia presenting with bony lesions alongside medullary involvement is rare with anecdotal reports having noted this manifestation in a newly diagnosed case. We here report an infrequent presentation of a young adult male presenting solely with multiple axial and pelvic bone lesions initially, with the initial impression being a lymphoma /infiltrative lesion. This is a case report that reiterates the need for prompt diagnosis and a thorough evaluation for early treatment, especially since this is a curable malignancy.

Pretreatment FDG- PET/CT imaging suggestive of vertebral lesion