Isolation of a diseased esophagus with surgical bypass is an acceptable treatment option[1-5] performed for various benign and malignant conditions affecting the esophagus with excellent outcome observed in patients following corrosive injury. There may be continued production of mucosal secretions within the native esophagus which gets retained and forms a mucocele. It is uncommon for a mucocele to develop in an esophagus sustaining caustic injury as the epithelium responsible for mucous production is also destroyed. These mucoceles are usually small and localized to a segment and remain asymptomatic without need of any surgical intervention. We herein present a case of middle aged female who underwent esophageal replacement for corrosive ingestion and now presented with chest pain two years after the surgery secondary to a huge mucocele involving the entire native esophagus.