FMT in Clostridium Difficile: Frozen or Fresh?

Submitted by sysadmin1 on Thu, 05/26/2016 - 15:01
Oncology, Gastroenterology and Hepatology Reports ,2017,6,1,43.
Published:November 2016
Type:Letter to Editor

FMT in Clostridium Difficile: Frozen or Fresh?

Adrija Hajra1, Dhrubajyoti Bandyopadhyay2

1Department of Internal Medicine, IPGMER, Kolkata, INDIA.

2Department of accident and emergency, Lady Hardinge Medical College, New Delhi, INDIA.

Abstract:

Pseudomembranous colitis is caused almost exclusively by toxins produced by Clostridium difficile (CD). There may be mild nonspecific diarrhea to severe colitis with toxic megacolon, perforation, and death.[1]

It is a well-known fact that Clostridium difficile infection (CDI) is a significant problem for patients as well as physicians. CDI recurrence is a more complicated issue. Limited treatment options and infection control issues make the condition worse. Though fecal microbiota transplantation (FMT) is a promising therapy, it is not readily available. Randomized, double-blind, noninferiority trial has been done to determine whether frozen-and-thawed FMT is noninferior to fresh FMT regarding clinical efficacy. Read more. . .

Keywords:Nil